Genetic variables, including genetic response to AAS, and quantities complicate the potential outcomes for any individual.
Quantities complicate, in that, “more usually consequents greater and severer side-effects.” Being overweight by 10 pounds isn’t a benefit to most individual’s health, but usually doesn’t risk or cause the same side effects in an individual as being 50 pounds overweight. Similarly, an individual cycling 300 mg/week of injectable testosterone for eight weeks, then dropping back to a physiological dose of 100 mg/week for the next ten weeks likely (“likely” not “definitely”) won’t risk or experience the same side effects which cycling 900 mg/week stacks for sixteen weeks then dropping back to 100 mg/week of testosterone alone for four weeks might.
Genetics complicate in that, due to the variation among individuals, some might be predisposed to health problems and risks which AAS amplify and/or accelerate.
No way to comprehensively predict health outcomes while using any dose larger than a typical therapeutic 100 mg/week of Test dose currently exists (and even the injectable form of TRT commonly elevates hematocrit). Reasonably then, the risks should be faced and carefully deliberated by any adult considering using AAS, without deflecting those risks by “how-about-ing” the risks of other issues such as being obese, heavy tobacco smoking, and couch-potatoing. The danger from choosing to cross a busy intersection without first looking both ways doesn’t dismiss the danger from choosing to take a walk outdoors during a lightning storm. Adults ought to be free to choose whether or not to use AAS, agreed; but, maturity should include choices based on rational, informed, honest assessment of both potential benefits and detriments.
Moderation and limitation of supra-therapeutic dosages might reduce risks to the equivalent of being 10 pounds overweight, yep. But, ultimately, AAS use is a version of playing russian roulette: more milligrams and longer cycles equal more bullets in the gun, but even at the minimum, there’s going to be one round that could potentially fire.