Here's what you need to know...
- Using large amounts of individual antioxidants can be damaging. It can interfere with muscle growth, recovery, and overall health.
- Taking large amounts of individual antioxidants doesn't quench free radicals. Instead, the antioxidants themselves turn into free radicals.
- Stress, smoking, alcohol, and pollution aren't the major cause of free radicals. Eating processed foods is a far more common cause.
- Antioxidant products like Pom Wonderful can bite you in the ass. You get nearly zero antioxidant benefit while the sugar itself causes a free radical tsunami.
- In order for them to work, antioxidants must be taken the way nature intended. You need to ingest a wide variety, from whole, minimally processed sources.
Antioxidants Can Negate the Effects of Exercise
My vote for the most persistent and damaging nutrition myth of all time is that free radicals are bad and antioxidants are good.
Sure, the production of free radicals – through pollution, sunlight, processed foods, exercise, or any one of hundreds of different ways – can be damaging, but free radicals are also essential to human health.
And yes, we need antioxidants to counter or buffer these free radicals but it's a delicate balancing act, and the way antioxidants are marketed to us and consequently used by us is mucking things up mightily. In fact, using antioxidants in the wrong way before, during, or after exercise can completely negate the beneficial effects of exercise. Worse, it can ruin your health.
A Drunk, Out-of-Control Friend
Patrick Mustain, writing in Scientific American, came up with a great analogy about free radicals and antioxidants that pretty much tells you everything you need to know. He explained that free radicals are molecules or atoms that contain an unpaired electron, and these electrons can't stand being alone; they're looking for company and that makes them highly reactive.
Mustain wrote that free radicals are like your drama-queen friend who gets embarrassingly drunk at a party, stumbles into things, breaks them, and in general creates a huge mess. Antioxidants, though, are the sober, loyal friend who corrals the drunken free radical, calms it down, gives it some coffee, and if necessary, holds its hair back while it upchucks into the commode.
In the body, this "drunken chaos" that the free radical might have caused manifests itself in the form of aging in general, heart disease, cancer, bad eyes, bad hair, bad skin, and internal organs that sputter along like horribly constructed Russian automobiles.
Antioxidants can prevent much of this from occurring, but that's not what's happening, at least not the way we use them in America. In fact, the way we use antioxidants paradoxically creates MORE free radicals, furthering the damage we were trying to ward off in the first place.
In effect, the sober friend who was supposed to keep the drunken drama queen from amping up the crazy just chugged a bottle of Jägermeister herself and became just as destructive as the drunkard.
Antioxidants: You're Using Them Wrong
The right kind of free radicals, in the right amount, and at the right time, are crucial to human health. Immune cells use free radicals as weapons against bacterial invaders.
Exercise itself generates free radicals, but these free radicals instruct cells to make their own antioxidants, which appear to be responsible for a lot of the health benefits derived from exercise. However, a study from a 2014 edition of Nutrition and Food Science concluded that the wrong type of antioxidant supplements can "abolish the beneficial effects of exercise."
And a 2006 British study found that using high amounts of a particular antioxidant (vitamin C) caused runners to lose muscle strength. Another found that exercisers using large amounts of vitamin C and E didn't experience the typical increase in insulin sensitivity usually associated with exercise.
You'll also find scores of studies to even suggest that indiscriminate antioxidant usage interferes with post-exercise muscle growth and recovery. What's infinitely worse, though, is that using antioxidants incorrectly can slowly erode your health and even significantly shorten your lifespan.
The problem doesn't have anything to do with the antioxidants in general, but the use of large amounts of single, over-hyped antioxidants and not in combination with thousands of their brethren, as you'd normally encounter by getting your antioxidants through whole-food sources.
Super-Dosing Individual Antioxidants is Bad News
Drs. Cleva Villanueva and Robert Kross, authors of a 2012 review on antioxidant-induced stress, insist that taking large amounts of a particular antioxidant, like vitamin C, actually creates more damaging free radicals.
Let's say you've just eaten some flaky cheddar biscuits that were sprinkled with the herb thyme. Cool, because the herb contains at least 30 known antioxidants. These antioxidants, like our analogy about the friend who helps her drunken friend, donate electrons to free radicals. Unfortunately, that turns the former antioxidant into a free radical itself.
No worries, though. It picks up an electron from another one of the antioxidants in the thyme, making the next one a free radical, too, only one that's less reactive than the first. This continues down the line, each antioxidant loaning an electron to another, summarily decreasing the damage they might otherwise do to proteins, lipids, or DNA.
But if there's only one antioxidant present, courtesy of the giant horse pill of a vitamin C tablet that ratcheted itself down your esophagus, there aren't any other antioxidants present to buffer it. You end up with potentially 1,000 mg. of additional free radicals, which is not what you intended.
It Gets Worse
Your mitochondria need free radicals to fine-tune the production of ATP, the energy currency of the cells. When you shut off or slow down free radical production through the introduction of large amounts of individual antioxidants, the membrane potential of the mitochondria collapses and it ends up spilling destructive, cell-killing proteins into the cell that houses the mitochondria.
Do this enough times to enough cells and you can do widespread damage to organs and, consequently, the body. Clearly, antioxidants need to be reconsidered and taken in a specific manner.
The Right Way to Get Your Antioxidants
If you were even vaguely conscious while reading this article, you've figured out that different types of antioxidants should be taken together, and the best way to do that is through the foods that contain them.
Be aware that there are thousands of antioxidants, and no conventional supplement, i.e., a drugstore "antioxidant formula" is going to do what you need it to do. It's quite likely these formulations wouldn't provide the buffering effect you get and need from ingesting multiple types of antioxidants at the same time.
To spell it out, you need to regularly ingest a large variety of fruits, vegetables, other foods that contain a variety of antioxidants, or a supplement like Superfood that's made of an array of whole foods (18 fruits and vegetables) that have simply been dried and powdered.
Other Things You Need to Know
Antioxidants Aren't Interchangeable
Antioxidants don't all work the same way. Vitamin C can't be replaced by vitamin E. Neither can virtually any of the thousands of antioxidants found in plant matter be substituted for one another.
Free radicals differ, just like antioxidants, so you need to take in a variety to do the job. Case in point, a 2006 study from Colorado State University found that people who ate a wide variety of plant matter had the most DNA protection.
Antioxidants Aren't Just in Fruits and Vegetables
Everything from the plant kingdom is rich in antioxidants. Whether they're beans, grains, seeds, or nuts, they're saturated with antioxidants. Even dairy and meat products, to a certain degree, contain antioxidants, depending on how much plant food was in the diets of the animals.
"Antioxidant Products" Can Be Ugly
While the pomegranate drink, POM Wonderful, might have some beneficial effects like stronger erections, they're probably not from the much ballyhooed antioxidants it contains.
One report says that we only absorb about 2/1000ths of the anthocynanins (a particular type of antioxidant plant chemical) POM Wonderful contains. What we do absorb from it efficiently, though, are 32 grams of sugar, which ironically causes more free radicals to be formed.
Stress, Smoking, and Pollution Aren't Necessarily the Main Producers of Free Radicals
Smoking, drinking (alcohol), and pollution are responsible for a good deal of the free radical stress our bodies are exposed to. However, not everyone smokes or drinks, and some people are lucky enough to breathe clean air.
However, almost everybody occasionally, if not regularly, eats processed food, which is arguably the worst generator of free radicals. Each and every bite is an assault on your health.
- Adams, Robert Benjamin; Egbo, Karen Nkechiyere; Demmig-Adams, Barbara, High-dose vitamin C supplements diminish the benefits of exercise in athletic training and disease prevention," Nutrition & Food Science, Volume 44, Number 2, 2014, pp. 95-101(7).
- Ede, Georgia, "The Antioxidant Myth," Psychology Today, Dec. 30, 2017.
- Mustain, Patrick, "Antioxidant Supplements: Too Much of a Kinda Good Things," Scientific American, Feb. 23, 2105.
- Villanueva, Cleva; Kross, Robert D. "Antioxidant-Induced Stress," Int J Mol Sci., Feb. 16, 2012.