An Easy Way to Build 4 Pounds of Extra Muscle

by TC Luoma

The Bedtime Protein Shake

It's a strategy everyone's talked about for years, but we never knew for sure if it worked. Now we do. Here's how to build muscle in bed.

We all kinda-sorta know that having a protein shake before going to bed is a good strategy to build muscle, but it’s still satisfying to read a scientific paper that says we’re not just right, but really right.

It’s particularly satisfying when that paper is a big review that looked at 45 papers on the subject and managed to draw some conclusions on how to best use the protein-drink-at-night strategy.

The Pre-Bed Protein Shake: All Muscle, No Fat

Tim Snijders, the lead author of the review, is no stranger to research on resistance training and bedtime protein ingestion. In 2015, he found that lifters who drank 28 grams of protein (14 grams of casein and 14 grams of casein hydrolysate) before bed gained about 4 more pounds of additional muscle than a control group over 12 weeks.

That’s damn impressive, and when he recently looked at the bulk of the papers on the subject, most agreed that drinking protein before bed increased muscle protein synthesis (MPS) dramatically without leading to any increases in fat.

Snijders wrote:

“All protein ingested prior to sleep is used for protein synthesis. When exercise is performed earlier that evening, a large part of ingested protein is directed to muscle protein synthesis and is not stored.”

It is true, however, that some of the studies he looked at didn’t show much or even any additional muscle protein synthesis overnight. But the researchers involved in those studies might’ve used insufficient amounts of protein, protein with a rotten biologic value (BV), or a resistance program more suited to sarcopenic poodles than bodybuilders or strength athletes.

Workout and Protein Timing

Is there something special about ingesting protein before bed? Or is it simply a matter of increasing total protein intake?

Here’s what Snijders thought about it:

“Despite a relatively high amount of protein ingested earlier in the day, pre-sleep protein ingestion would presumably still provide an anabolic stimulus on overnight muscle protein synthesis rates, thereby enhancing daily muscle tissue re-conditioning.”

Another possible question arises from the timing of the resistance training. In some of the studies where they found a positive association between bedtime protein and additional muscle protein synthesis, the resistance training took place in the evening between 8:00 and 10:00 PM.

That’s promising for lifters who hit the gym in the evening, but what about lifters who work out in the morning or late afternoon? While the answers aren’t yet clear, my guess is that the late afternoon trainers would still be in their anabolic “window” at bedtime and would still benefit from drinking some additional protein before hitting the sack.

Morning trainees would also benefit from late-night protein in general, but whether they’d enjoy the same dramatic increases in muscle protein synthesis is unknown (they might simply benefit from adding to their total protein intake rather than a time-sensitive increase in MPS).

If you do train in the morning, you could try a little experiment. Save some or all of your arm training for the evening when you’re watching TV. Pull out a pair of dumbbells and do a few sets of 10-6-10 training. Then, drink your bedtime protein and observe what, if anything, happens to your arms over several weeks.

What Do I Drink and How Much?

Drink a high-quality shake containing casein before bed. Most of the studies used casein, probably because it’s a slower-digesting protein, so it’s not known how well other proteins would fare in similar circumstances. Metabolic Drive (Buy at Amazon), which uses superior micellar casein, is the ideal choice.

When? Between 10 and 30 minutes before retiring. How much? Up to 60 grams, but the average sweet spot seems to be around 30 grams.

MD-Buy-on-Amazon

References

References

  1. Snijders T et al. Protein Ingestion before Sleep Increases Muscle Mass and Strength Gains during Prolonged Resistance-Type Exercise Training in Healthy Young Men. J Nutr. 2015 Jun;145(6):1178-84. PubMed.
  2. Snijders T et al. The Impact of Pre-sleep Protein Ingestion on the Skeletal Muscle Adaptive Response to Exercise in Humans: An Update. Front Nutr. 2019 Mar 6;6:17. PubMed.
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Years ago when I was training more vigorously, I added a bedtime protein shake to my diet. I don’t remember if it was micellar or whey protein but sure enough, I rapidly gained 4 LBS.

I can’t know if it was all muscle, but it is interesting that that 4 LBS that I have always remembered and taken for granted as a positive benefit of bedtime protein is the result of this study.

Here’s another find. There’s a lot of opportunity to look at benefits not just for the typical “young men” but older athletes too.
So:
though these authors in 2023 say:
In a recently published study, we reported no beneficial effect of protein ingestion (20 g whey + 1 g leucine) immediately after exercise and prior to sleep on the increase in skeletal muscle mass and strength during 12 weeks of resistance-type exercise training in healthy older men (44).

And likewise
"Effects of pre-sleep protein consumption on muscle-related outcomes - A systematic review - PubMed
the authors are more cautious:
In elderly, despite the initial evidence regarding the pre-sleep protein enhances overnight muscle protein synthesis rates, the current available evidence is limited precluding to conclude about the chronic effects on skeletal muscle mass or strength.

work in 2022 found that there was a benefit: exercise before bedtime, then some protein is a go for older men when combined with resistance exercise
see:
Exercise Plus Presleep Protein Ingestion Increases Overnight Muscle Connective Tissue Protein Synthesis Rates in Healthy Older Men - PubMed

More specific benefits: Casein/Whey - doesn’t seem to matter
the effects in mitochondrial and myofibrial are good, no matter what kind of protein used - whey/casein - doesn’t matter (they added some carbs in this mix which muddies the water a bit, but interesting) Myofibrillar and Mitochondrial Protein Synthesis Rates Do Not Differ in Young Men Following the Ingestion of Carbohydrate with Milk Protein, Whey, or Micellar Casein after Concurrent Resistance- and Endurance-Type Exercise - PubMed

what this supplementation does not seem to do is aid in recovery for the next day but maybe one is less hungry in the am
Pre-sleep protein supplementation after an acute bout of evening resistance exercise does not improve next day performance or recovery in resistance trained men - PubMed

Overnight fast - except for small protein shot
final note? for most other nutrients - aka having a meal before bed - the idea is not to add load to the repair processes that take place during sleep (including protein synthesis for muscles) - and yet it seems that small amounts particularly of protein have this beneficial side effect. and not just for athletes but seemingly across the board - not least when combined with exercise
The Health Impact of Nighttime Eating: Old and New Perspectives - PMC
where the authors state
nighttime consumption of small (~150 kcals) single nutrients or mixed-meals does not appear to be harmful and may be beneficial for muscle protein synthesis and cardiometabolic health. Future research is warranted to elucidate potential applications of nighttime feeding alone and in combination with exercise in various populations of health and disease.”

That means overnight fasting still seems critical for overall repair - with the exception of a small bolus of protein WHEN precursed by a likewise small dose of resistance work.

COOL!

-m.c.

3 Likes

Really? 4, just like the study? That’s wild.

Yes, it was EXACTLY 4 LBS.
Like I said, such a large gain in a short time with no other changes made enough impact that I’ve never forgotten it after more than 20 years.

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I do most of my workouts in the AM, but I have found a bowl of low fat cottage cheese (~30g protein) with some blueberries within a hour or so of going to bed makes me sleep like a baby and seems to enhance my recovery (this is on top of what mag glycinate, melatonin, and other various items have helped). I don’t do it every night due to many variables, but its enough of an effect that when I am getting run down its the first thing I try to turn my recovery around.

2 Likes

I’ve been using the pre-bed protein shake AND I’ve even taken to having a middle of the night protein shake and I feel like the latter has been an even BIGGER boon. Before bed, I mix up a shake of 1 scoop of Metabolic Drive and 1 raw egg with some salt in water and ice, put it at my bathroom sink, and I inevitably wake up in the middle of the night BECAUSE of the pre-bed shake to pee, after which point I have my “wake-and-shake” shake and go back to bed. I sleep so peacefully with a belly full of yummy vanilla protein, and actually find that training “fasted” in the morning isn’t an issue with those nutrients in me.

Easy muscle indeed!

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Good tip! Thanks!

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Cool, but why the raw egg and salt?

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I used to do this ages ago but I could never tell if it made a difference so I quit. Now I take my collagen, superfood, creatine, etc. shake right before bed. Probably not optimal for muscle building, but at least I’m getting some protein in.

Raw egg just to add in some of the healthy fats and various other benefits that come with whole eggs (I get pasture raised, so they’re just super ridiculous), salt because I keep my carbs low and find salt very hlpeful in maintaining electrolyte balance. It also enhances the flavor.

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I did this at the beginning of the pandemic with collagen protein and fiber. I dont recall what i gained but i didnt change my diet. i recall losing like 4% bf and only losing like 3lbs while looking noticeably more muscular. Its a nifty little trick

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With collagen? Interesting.

Several years ago I would have half a serving of a meal replacement supplement before bed.
Not certain if had casein protein but it was balanced. At the time it was part of my ingestion of good foods 6 times per day. I was involved in a transformation contest. Strict bf measurements and weight at beginning and end of 12 weeks. When I think about I still cannot believe the numbers even to this day. I reduced body fat by 8% and packed on 27 lbs of muscle in 12 weeks. I know this sound not possible but is the honest to god truth. Was laser focused on efficient short training sessions and disciplined with diet. I think this revelation of casein at night is accurate. Keeping flow of Positive nitrogen balance is key in my opinion


I used this specifically

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Have you tried to replicate the results? (It’d be unlikely you’d be as successful again, but be interesting to see how well it worked.)

I use collagen, too – just not before bed. I’ll consider adopting your tactic.

I have attempted for must shorter period of time, lost interest to be honest. It took a quite a lot of effort and was tiresome to eat 3500-4000 calories a day. That was 25 years ago. No at 65 if I ate those kind of calories I may end up looking like porky pig.
It would however be interesting to see if I could have similar results at my age. I have maintained that weight and approx same body weight with slightly higher bf. I work harder in gym than I did when I was in my 20s. Comfortable where I am but never satisfied. Have continued to increase muscle over time. It is said you can’t build muscle as older man is a person who is not informed or lazy. I am 6-2 ,210lbs at 11% bf , train 7 days per week.

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Before bed is apparently a good time to take it – especially if you add extra Glycine like I think I read in one of your articles – because it helps with sleep.

Pathogens in your Smoothies?
Does your blender have a gasket?
Do you remove it and clean and dry both the gasket and the wet spot, which is the overnight breeding ground for pathogens to be whipped into the next healthy blend.
https://www.themichaelrubino.com/how-to-prevent-a-mold-in-a-blender-to-avoid-an-icky-health-hazard/